São Tomé ‒ São Tomé and Príncipe has made remarkable strides against malaria. Over the past five years, only two malaria-related deaths have been recorded in the country.
In the first quarter of 2025, the country registered 1293 malaria cases and no deaths. The Autonomous Region of Príncipe, the smaller of the two main islands that constitute São Tomé and Príncipe, registered just three cases of malaria as of March 2025, compared with nine in the same period the year before.