The mission of the General Management and Coordination (GMC) Cluster is to facilitate and enable the implementation of WHO's global health mandate in the African region. This is achieved through effective and responsive administrative and managerial support to the Technical Clusters and country offices, all while maintaining a robust internal control environment.

Public health emergencies in the African Region present a complex and multifaceted challenge that demands a comprehensive and collaborative response. The Region carries the highest burden of public health emergencies globally, with over 100 major events reported each year.