Public health emergencies in the African Region present a complex and multifaceted challenge that demands a comprehensive and collaborative response. The Region carries the highest burden of public health emergencies globally, with over 100 major events reported each year.

The WHO/AFRO Health Promotion, Disease Prevention and Control (DPC) Cluster was established in 2025 to better integrate the AFRO disease prevention and control programs within a health system strengthening framework through a data-centric, results-focused, and integrated cluster management approach.