Juba – South Sudan faces recurring public health threats from infectious disease outbreaks to climate-related emergencies such as floods, drought and heat waves. As of August 2025, South Sudan had active outbreaks of Anthrax, Cholera, Circulating Vaccine Derived Polio Virus Type 2 (cVDPV2), Viral Hepatitis E, Measles and Mpox. At the same time, floods had inundated 16 health facilities and displaced more than 56,000 households with nearly 200,000 people.