Ebola virus disease in Guinea (Situation as of 25 March 2014)

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25 March 2014 - The Ministry of Health (MoH) of Guinea has notified WHO of a rapidly evolving outbreak of Ebola virus disease in forested areas south eastern Guinea. The cases have been reported in Guekedou, Macenta, and Kissidougou districts. As of 25 March 2014, a total of 86 suspected cases including 60 deaths (case fatality ratio: 69.7%) had been reported. Four health care workers are among the victims. Reports of suspected cases in border areas of Liberia and Sierra Leone are being investigated.

Thirteen of the cases have tested positive for Ebola virus by PCR (six at the Centre International de Recherche en Infectiologie (CIRI) in Lyon, France, and seven at the Institut Pasteur Dakar, Senegal), confirming the first Ebola virus disease outbreak in Guinea. Results from sequencing done by CIRI Lyon showed strongest homology of 98% with Zaire Ebolavirus last reported in 2009 in Kasai-Occidental Province of DR Congo. This Ebolavirus species has been associated with high mortality rates during previous outbreaks.

The MOH together with WHO and other partners are implementing measures to control the outbreak and prevent further spread. The MoH has activated the national, provincial and district emergency management committees to coordinate response. The MoH has also advised the public to take measures to avert the spread of the disease and to report any suspected cases.

Multidisciplinary teams have been deployed to the field to strengthen surveillance, sensitize and educate the public, manage case and implement appropriate infection prevention and control measures in health facilities and communities affected. The MOH and MSF have established isolation facilities in Guéckédou district, and plans are underway to establish an additional isolation ward in Macenta district.

The Emerging and Dangerous Pathogens Laboratory Network (EDPLN) is working with the Guinean VHF Laboratory in Donka, the Institut Pasteur in Lyon, the Institut Pasteur in Dakar, and the Kenema Lassa fever laboratory in Sierra Leone to make available appropriate Filovirus diagnostic capacity in Guinea and Sierra Leone. Additional laboratory capacity is being established with the deployment of mobile laboratories supported by international partners.

WHO and other partners are deploying additional experts to provide support to the Ministry. The necessary supplies and logistics required for supportive management of patients and all aspects of outbreak control are also being mobilized. The MOH is also preparing a request to the African Public Health Emergency Fund (APHEF) as well as to other potential donors to support outbreak response. APHEF supports timely deployment of rapid response teams during outbreaks and emergencies, and procurement and prepositioning of epidemic and emergency response supplies.

WHO does not recommend that any travel or trade restrictions be applied to Guinea in respect to this event.


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